Terbinafine is an antifungal drug prescribed for treating a range of fungal infections.
Uses
Fungal Infections: It is commonly used to treat fungal infections of the skin, hair, and nails, such as:
- Athlete’s Foot (Tinea Pedis)
- Ringworm (Tinea Corporis)
- Jock Itch (Tinea Cruris)
- Fungal Nail Infections (Onychomycosis)
Forms
- Topical: Creams, gels, or sprays for skin infections.
- Oral: Tablets or granules for more severe or systemic infections, such as nail infections.
How It Works
Terbinafine belongs to the allylamine class of antifungals.
It works by inhibiting an enzyme called squalene epoxidase, which is essential for the production of ergosterol, a key component of fungal cell membranes. This disrupts the fungal cell membrane, leading to fungal cell death.
Dosage
- Topical: Applied once or twice daily to the affected area for 1–4 weeks, depending on the infection.
- Oral: Typically taken once daily for 6–12 weeks for nail infections, or shorter durations for skin infections.
Side Effects
- Topical: Mild skin irritation, itching, or redness at the application site.
- Oral:
- Common: Headache, gastrointestinal issues (nausea, diarrhea, abdominal pain), taste disturbances.
- Rare but serious: Liver problems, severe skin reactions, blood disorders.
Precautions
- Inform your doctor if you have liver disease, as terbinafine can affect liver function.
- Regular liver function tests may be required during prolonged oral treatment.
- Avoid alcohol while taking terbinafine to reduce the risk of liver damage.
Interactions
Terbinafine may interact with other medications, such as:
- Caffeine
- Cyclosporine
- Certain antidepressants (e.g., SSRIs)
- Beta-blockers
Always update your doctor on all medications and supplements you are using.
Effectiveness
- Terbinafine is highly effective for fungal infections, especially nail infections, with a cure rate of around 70–80% when taken orally.
Pregnancy and Breastfeeding
- Not advised during pregnancy or breastfeeding unless deemed essential by a doctor. Consult a doctor for advice.
If you have been prescribed terbinafine, follow your healthcare provider’s instructions carefully and report any unusual symptoms.