Alfuzosin is a prescription medication used to treat symptoms of an enlarged prostate, also known as benign prostatic hyperplasia (BPH). It helps men urinate more easily by relaxing muscles in the urinary tract.
What Alfuzosin Does
- Alfuzosin belongs to a class of drugs called alpha-1 blockers.
- It targets alpha-1 receptors in the prostate, bladder neck, and urethra, causing muscles to relax.
- This relaxation makes it easier to start urinating and reduces urgency or dribbling.
Who It’s For (Indications)
Alfuzosin is used to treat symptoms of BPH, including:
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- Difficulty starting urination
- Weak urine stream
- Frequent urination, especially at night
- Sudden urgency to urinate
How to Take Alfuzosin
- Available as extended-release 10 mg tablets, typically taken once per day.
- Take it with food to increase absorption.
- Do not crush or chew the tablet — swallow it whole.
Possible Side Effects
Common:
- Dizziness
- Fatigue
- Headache
- Nasal congestion
Serious (but rare):
- Fainting due to low blood pressure
- Prolonged erection (priapism)
- Severe allergic reaction (rash, swelling, breathing issues)
Precautions and Warnings
- Not recommended for patients with severe liver or kidney disease.
- Use caution if you have low blood pressure or are on medications that lower blood pressure.
- Tell your doctor if you have heart problems, especially a history of angina or arrhythmias.
Contraindications
- Do not use if you’ve had an allergic reaction to alfuzosin or similar alpha-blockers.
- Avoid use in cases of moderate to severe liver impairment.
Drug Interactions
Alfuzosin may interact with:
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- Other alpha-blockers (e.g., doxazosin, tamsulosin)
- Blood pressure medications
- Liver enzyme inhibitors (CYP3A4) like ketoconazole, ritonavir, or erythromycin
Special Populations
- Not approved for use in women or children.
- Pregnant or breastfeeding individuals should not use this medication.
- Only for adult men diagnosed with BPH.
Final Thoughts
Alfuzosin is an effective treatment for urinary symptoms caused by an enlarged prostate. It’s generally well tolerated, but should be taken exactly as prescribed to avoid complications. Always consult your healthcare provider before starting or changing your medications. If you experience side effects or new symptoms, contact a doctor immediately.