Metformin + Glimepiride
Composition
Metformin + Glimepiride is a synergistic combination of two oral antidiabetic agents commonly used in the LATAM region. Metformin, a biguanide, reduces hepatic glucose production and enhances insulin sensitivity, while Glimepiride, a sulfonylurea, stimulates insulin secretion from the pancreas. Together, they effectively manage blood sugar levels in patients with type 2 diabetes.
Indications
This combination is indicated for the management of type 2 diabetes mellitus, especially in patients who do not achieve adequate glycemic control with diet and exercise alone.
Side effects
Common side effects may include gastrointestinal issues such as nausea, vomiting, and diarrhea. Other potential side effects include hypoglycemia (low blood sugar), allergic reactions, dizziness, and lactic acidosis in patients with renal impairment.
Precautions
Common side effects may include gastrointestinal issues such as nausea, vomiting, and diarrhea. Other potential side effects include hypoglycemia (low blood sugar), allergic reactions, dizziness, and lactic acidosis in patients with renal impairment.
Contraindications
Metformin + Glimepiride is contraindicated in patients with severe renal impairment, acute or chronic metabolic acidosis, and known hypersensitivity to either component. It should be avoided in patients with diabetic ketoacidosis and during pregnancy and breastfeeding unless specifically directed by a physician.
Dosage and administration
As directed by the physician.
Countries
Metformin + Glimepiride is widely available in various LATAM countries, including Peru, Venezuela, Ecuador, Colombia, and Chile.
Available Forms
The combination is available in various forms, including tablets in different strengths to suit individualized treatment regimens.
Manufacturing Services
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