Human Fibrin Sealant
Composition
Contains human-derived fibrinogen and thrombin components that mimic the final steps of the coagulation cascade to form a fibrin clot.
Indications
Used as a topical hemostatic agent to control bleeding during surgery or trauma when conventional methods are ineffective or impractical.
Side effects
Allergic reactions, risk of viral transmission (very low with modern processing), local inflammation.
Precautions
Use only topically; avoid intravascular injection. Screen for hypersensitivity; ensure sterility to reduce infection risk.
Contraindications
Known allergy to human plasma proteins or sealant components.
Dosage and administration
Apply directly to bleeding site during surgery; dosage varies by product and bleeding severity.
Countries
Available Forms
Two-component kits containing separate fibrinogen and thrombin solutions, usually supplied as vials or prefilled syringes.