Usage of ceftriaxone is indicated in the treatment of acute bacterial otitis media, intra-abdominal infections, pelvic inflammatory disease, septic shock, skin structure-related infections, severe acute bacterial rhinosinusitis, sinusitis, soft tissue necrotizing infections, prosthetic joint infections, epiglottitis, and acute epididymitis.

Mild to moderate side effects have been observed. Side effects such as nausea, diarrhea, elevated liver enzymes, dizziness, anemia, excessive sweating, flushing, Headache, rash, change in taste, loss of appetite, overactive reflexes, and upset stomach.

This drug is to be prescribed with caution in patients with gastrointestinal diseases, immune-mediated disorders, superinfections, Clostridium difficile-associated diarrhea, pancreatitis, or biliary obstruction.

This drug is contraindicated in patients with a history of hypersensitivity to it or any other drugs or members of the cephalosporin class.

The typical adult dosage is 1 gram intravenous route administered 12 hours per day.

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