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Proguanil

Composition

Proguanil hydrochloride, a folate antagonist.

Indications

Malaria prevention and treatment (often with atovaquone).

Side effects

Mouth ulcers, GI upset.

Precautions

Monitor for resistance.

Contraindications

Severe renal impairment.

Dosage and administration

Oral, often in fixed combination.

Countries

Available Forms

Tablets (alone or with atovaquone).