Edoxaban

Used to prevent stroke and systemic embolism in non-valvular atrial fibrillation, and to treat and prevent deep vein thrombosis (DVT) and pulmonary embolism (PE).

Bleeding, anemia, rash, elevated liver enzymes.

Use with caution in patients with renal impairment or bleeding risk; avoid abrupt discontinuation to prevent thrombotic events.

Active pathological bleeding, mechanical heart valves, severe hepatic impairment.

Typical dose: 30–60 mg orally once daily depending on indication and renal function.

Oral tablets.