Desmopressin
Composition
Contains Desmopressin Acetate, a synthetic analog of vasopressin; strengths vary by form (e.g., 0.1 mg, 0.2 mg tablets).
Indications
Used to treat diabetes insipidus, nocturnal enuresis (bedwetting), and bleeding disorders like mild hemophilia A and von Willebrand disease.
Side effects
Headache, nausea, hyponatremia, facial flushing, water retention.
Precautions
Monitor serum sodium; use cautiously in patients at risk of fluid overload or electrolyte imbalance.
Contraindications
Hyponatremia, moderate to severe renal impairment, SIADH, or hypersensitivity to Desmopressin.
Dosage and administration
Varies by indication; for nocturnal enuresis: 0.2–0.6 mg orally at bedtime; for DI: oral, intranasal, or injectable routes.
Countries
Available Forms
Oral tablets, sublingual tablets (melts), intranasal spray, and injectable solution.